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KMID : 0370219860300060294
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Yakhak Hoeji
1986 Volume.30 No. 6 p.294 ~ p.300
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Synthesis and Antibacterial Activities of New β-Lactam Compounds
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Abstract
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New antibiotics having moieties of penicillanic acid, cephalosporanic acid and ampicillin on both ends of the central polyalkylene were synthesized by reacting 6-aminopenicillanic acid (6-APA1), 7-amino cephalosporanic acid (7-ACA) and ampicillin with hexamethylene diisocyanate and sebacoyl chloride, respecetively. Antibiacterial activities of the compounds were also investigated.
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